Pub. Date : 2013 Jul-Aug
PMID : 23806019
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of hOGG1 over-expression on cisplatin resistance in esophageal squamous carcinoma cells. | Cisplatin | 8-oxoguanine DNA glycosylase | Homo sapiens |
| 2 | In this article, the effect of hOGG1 over-expression on cisplatin resistance in esophageal squamous cell carcinoma (ESCC) EC9706 and ET13 cells was investigated. | Cisplatin | 8-oxoguanine DNA glycosylase | Homo sapiens |
| 3 | After exposure to a common chemotherapeutic agent cisplatin, hOGG1 over-expression cells exhibited longer survival ability, lower cell apoptosis, and less 8-oxoG oxidative damage, compared with vector-treated cells and no-treated cells (p<0.05). | Cisplatin | 8-oxoguanine DNA glycosylase | Homo sapiens |
| 4 | The findings implied that over-expression of hOGG1 can protect ESCC cells from cisplatin-induced apoptosis and prolong cancer cell survival time. | Cisplatin | 8-oxoguanine DNA glycosylase | Homo sapiens |