Title : Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease.

Pub. Date : 2013 Jul

PMID : 23801739






1 Functional Relationships(s)
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1 Furthermore, in agreement with the improvements observed in motor function beclin 1 overexpression prevented neuronal dysfunction and neurodegeneration, decreasing formation of polyglutamine-expanded aggregates, preserving Purkinje cell arborization and immunoreactivity for neuronal markers. polyglutamine beclin 1, autophagy related Mus musculus