Title : Androgen metabolite-dependent growth of hormone receptor-positive breast cancer as a possible aromatase inhibitor-resistance mechanism.

Pub. Date : 2013 Jun

PMID : 23780684






2 Functional Relationships(s)
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Protein Name
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1 5alpha-Androstane-3beta,17beta-diol (3beta-diol) generated from DHT by 3beta-hydroxysteroid dehydrogenase type 1 (HSD3B1) shows androgenic and substantial estrogenic activities, representing a potential mechanism of AI resistance. 17beta-diol hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Mus musculus
2 5alpha-Androstane-3beta,17beta-diol (3beta-diol) generated from DHT by 3beta-hydroxysteroid dehydrogenase type 1 (HSD3B1) shows androgenic and substantial estrogenic activities, representing a potential mechanism of AI resistance. 17beta-diol hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Mus musculus