Protein Name | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
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Organism | Mus musculus |
Gene ID | 15492 |
Gene Symbol | Hsd3b1 |
UniProt | P24815 (3BHS1_MOUSE), Q3UI20 (Q3UI20_MOUSE), Q3UJ12 (Q3UJ12_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
23
Total Number of Articles : 20 |
Description |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
Gene Summary |
Predicted to enable 3-beta-hydroxy-delta5-steroid dehydrogenase activity and steroid delta-isomerase activity. Predicted to be involved in several processes, including C21-steroid hormone metabolic process; hippocampus development; and response to corticosterone. Predicted to act upstream of or within steroid metabolic process. Located in mitochondrion. Is expressed in several structures, including endocrine gland; genitourinary system; liver; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Apr 2022] |
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