Title : IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation.

Pub. Date : 2013 Aug 29

PMID : 23777768






1 Functional Relationships(s)
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1 The presence of an iron-responsive element (IRE) within the 5" untranslated region of HIF2alpha mRNA suggests a further iron- and oxygen-dependent mechanism for translational regulation of its expression via iron regulatory proteins 1 and 2 (IRP1 and IRP2, respectively). Oxygen endothelial PAS domain protein 1 Mus musculus