Title : [How I treat ... with metformin a diabetic patient with moderate renal insufficiency].

Pub. Date : 2013 Apr

PMID : 23755710






1 Functional Relationships(s)
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1 Metformin, the first choice oral glucose-lowering agent, is classically contraindicated in case of chronic kidney disease of stages 3-5 (creatinine clearance < 60 ml/min/1.73 m2), because of a risk of accumulation of the biguanide that may lead to lactic acidosis. Metformin CD59 molecule (CD59 blood group) Homo sapiens