Title : Tryptamine and dimethyltryptamine inhibit indoleamine 2,3 dioxygenase and increase the tumor-reactive effect of peripheral blood mononuclear cells.

Pub. Date : 2013 Jul

PMID : 23754498






3 Functional Relationships(s)
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1 We conclude that the IDO inhibition by TRY and DMT contributed to a more effective tumor-reactive response by the PBMCs. N,N-Dimethyltryptamine indoleamine 2,3-dioxygenase 1 Homo sapiens
2 The aim of this study was to identify whether the metabolites originated from the competitive routes of tryptophan metabolism, such as the serotonergic or N, N-dimethyltryptamine (DMT) pathways, have inhibitory effects on recombinant human IDO (rhIDO) activity. N,N-Dimethyltryptamine indoleamine 2,3-dioxygenase 1 Homo sapiens
3 The aim of this study was to identify whether the metabolites originated from the competitive routes of tryptophan metabolism, such as the serotonergic or N, N-dimethyltryptamine (DMT) pathways, have inhibitory effects on recombinant human IDO (rhIDO) activity. N,N-Dimethyltryptamine indoleamine 2,3-dioxygenase 1 Homo sapiens