Pub. Date : 2013
PMID : 23738323
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, mollugin induced the activation of p38, ERK, and JNK and the expression of heme oxygenase-1 (HO-1) and nuclear factor E2-related factor 2 (Nrf2). | rubimaillin | heme oxygenase 1 | Homo sapiens |
| 2 | Furthermore, mollugin induced the activation of p38, ERK, and JNK and the expression of heme oxygenase-1 (HO-1) and nuclear factor E2-related factor 2 (Nrf2). | rubimaillin | heme oxygenase 1 | Homo sapiens |
| 3 | Mollugin-induced growth inhibition and apoptosis of HO-1 were reversed by an HO-1 inhibitor and Nrf2 siRNA. | rubimaillin | heme oxygenase 1 | Homo sapiens |
| 4 | Mollugin-induced growth inhibition and apoptosis of HO-1 were reversed by an HO-1 inhibitor and Nrf2 siRNA. | rubimaillin | heme oxygenase 1 | Homo sapiens |
| 5 | Collectively, this is the first report to demonstrate the effectiveness of mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- kappa B. | rubimaillin | heme oxygenase 1 | Homo sapiens |