Pub. Date : 2013
PMID : 23737956
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, UA treatment induced colon cancer cell apoptosis, increased the cleavage of PARP, caspase-3 and 9, and trigged the release of cytochrome c from mitochondrial inter-membrane space into cytosol. | ursolic acid | cytochrome c, somatic | Homo sapiens |
| 2 | These results indicate that UA inhibits cell proliferation and induces apoptosis in colon cancer cells through simultaneous modulation of the multiple signaling pathways such as MMP9/CDH1, Akt/ERK, COX-2/PGE2, p300/NF-kappaB/CREB2, and cytochrome c/caspase pathways. | ursolic acid | cytochrome c, somatic | Homo sapiens |