Title : Loss of heterozygosity in the fragile histidine triad (FHIT) locus and expression analysis of FHIT protein in patients with breast disorders.

Pub. Date : 2013

PMID : 23724516






3 Functional Relationships(s)
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1 Loss of heterozygosity in the fragile histidine triad (FHIT) locus and expression analysis of FHIT protein in patients with breast disorders. Histidine fragile histidine triad diadenosine triphosphatase Homo sapiens
2 PURPOSE OF INVESTIGATION: The fragile histidine triad (FHIT) gene is a tumor suppressor frequently inactivated in various types of tumors. Histidine fragile histidine triad diadenosine triphosphatase Homo sapiens
3 The changes in the locus of the FHIT gene occur with greater frequency in the coded region of the gene, principally near exons 5 and 8, where the FRA3B site and the histidine triad respectively are found. Histidine fragile histidine triad diadenosine triphosphatase Homo sapiens