Title : [Effect of icariin on the expression of receptor activator nuclear factor-κB ligand and osteoprotegerin of human periodontal ligament cells].

Pub. Date : 2013 Feb

PMID : 23714056






5 Functional Relationships(s)
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1 [Effect of icariin on the expression of receptor activator nuclear factor-kappaB ligand and osteoprotegerin of human periodontal ligament cells]. icariin TNF receptor superfamily member 11b Homo sapiens
2 OBJECTIVE: To investigate the effect of icariin on the expression of receptor activator nuclear factor-kappaB ligand (RANKL) and osteoprotegerin (OPG) of human periodontal ligament cells (hPDLC) inhibited by sonicated extracts of Porphyromonas gingivalis (Pg). icariin TNF receptor superfamily member 11b Homo sapiens
3 OBJECTIVE: To investigate the effect of icariin on the expression of receptor activator nuclear factor-kappaB ligand (RANKL) and osteoprotegerin (OPG) of human periodontal ligament cells (hPDLC) inhibited by sonicated extracts of Porphyromonas gingivalis (Pg). icariin TNF receptor superfamily member 11b Homo sapiens
4 Compared with control group, RANKL and OPG expression changed in groups stimulated with 0.001, 0.01, 0.1, 1 mg/L icariin. icariin TNF receptor superfamily member 11b Homo sapiens
5 CONCLUSIONS: The concentration of 0.1 mg/L icariin can inhibit hPDLC expression of RANKL in sonicated extracts of Pg and promote OPG expression. icariin TNF receptor superfamily member 11b Homo sapiens