Title : A feedback loop in PPARγ-adenosine A2A receptor signaling inhibits inflammation and attenuates lung damages in a mouse model of LPS-induced acute lung injury.

Pub. Date : 2013 Sep

PMID : 23712033






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Instead of directly interacting with PPARgamma, A2AR stimulated PPARgamma expression via protein kinase A (PKA)-cAMP response element binding protein (CREB) signaling by provoking the binding of CREB to a cAMP responsive element (CRE)-like site in PPARgamma gene promoter region. Cyclic AMP peroxisome proliferator activated receptor gamma Mus musculus
2 Instead of directly interacting with PPARgamma, A2AR stimulated PPARgamma expression via protein kinase A (PKA)-cAMP response element binding protein (CREB) signaling by provoking the binding of CREB to a cAMP responsive element (CRE)-like site in PPARgamma gene promoter region. Cyclic AMP peroxisome proliferator activated receptor gamma Mus musculus
3 Instead of directly interacting with PPARgamma, A2AR stimulated PPARgamma expression via protein kinase A (PKA)-cAMP response element binding protein (CREB) signaling by provoking the binding of CREB to a cAMP responsive element (CRE)-like site in PPARgamma gene promoter region. Cyclic AMP peroxisome proliferator activated receptor gamma Mus musculus
4 Instead of directly interacting with PPARgamma, A2AR stimulated PPARgamma expression via protein kinase A (PKA)-cAMP response element binding protein (CREB) signaling by provoking the binding of CREB to a cAMP responsive element (CRE)-like site in PPARgamma gene promoter region. Cyclic AMP peroxisome proliferator activated receptor gamma Mus musculus