Pub. Date : 2013 Aug
PMID : 23710625
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the syngeneic Lewis-to-Lewis rat model of kidney transplantation, xenon exposure to donors before graft retrieval or to recipients after engraftment decreased caspase-3 expression, localized HMGB-1 within nuclei and prevented TLR-4/NF-kappaB activation in tubular cells; serum pro-inflammatory cytokines IL-1beta, IL-6 and TNF-alpha were reduced and renal function was preserved. | Xenon | interleukin 6 | Rattus norvegicus |