Title : Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells.

Pub. Date : 2013 Oct

PMID : 23707663






2 Functional Relationships(s)
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1 RESULTS: Inhibition of CYP2E1 with 10muM diallyl sulfide most effectively led to decreases in the oxidative stress and toxicity as compared with ADH inhibition with 2mM pyrazole or the combined inhibition of ADH and CYP2E1 with 5mM 4-methyl pyrazole. allyl sulfide cytochrome P450 family 2 subfamily E member 1 Homo sapiens
2 RESULTS: Inhibition of CYP2E1 with 10muM diallyl sulfide most effectively led to decreases in the oxidative stress and toxicity as compared with ADH inhibition with 2mM pyrazole or the combined inhibition of ADH and CYP2E1 with 5mM 4-methyl pyrazole. allyl sulfide cytochrome P450 family 2 subfamily E member 1 Homo sapiens