Title : Cinacalcet lowering of serum fibroblast growth factor-23 concentration may be independent from serum Ca, P, PTH and dose of active vitamin D in peritoneal dialysis patients: a randomized controlled study.

Pub. Date : 2013 May 25

PMID : 23705925






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1 Cinacalcet lowering of serum fibroblast growth factor-23 concentration may be independent from serum Ca, P, PTH and dose of active vitamin D in peritoneal dialysis patients: a randomized controlled study. Cinacalcet fibroblast growth factor 23 Homo sapiens
2 Additionally, we analyzed change in FGF23 levels between two treatments to explore the cinacalcet effect in lowering FGF23. Cinacalcet fibroblast growth factor 23 Homo sapiens
3 After treatment, cinacalcet group experienced a significant reduction in FGF23 levels (median value from 3,960 to 2,325 RU/ml, P = 0.002), while an insignificant change was shown for control group (from 2,085 to 2,415 RU/ml). Cinacalcet fibroblast growth factor 23 Homo sapiens
4 After adjustment, cinacalcet treatment was independently associated with the serum FGF23 reduction. Cinacalcet fibroblast growth factor 23 Homo sapiens
5 CONCLUSION: Cinacalcet treatment was independently associated with the reduction of FGF23 in our PD patients. Cinacalcet fibroblast growth factor 23 Homo sapiens