Title : Transactivation of ErbB receptors by leptin in the cardiovascular system: mechanisms, consequences and target for therapy.

Pub. Date : 2014

PMID : 23688012






1 Functional Relationships(s)
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1 Recent experimental studies indicate that chronically elevated leptin transactivates the EGFR through the mechanisms requiring reactive oxygen species and cytosolic tyrosine kinase, c-Src. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens