Title : Structure-activity relationship of N,N'-disubstituted pyrimidinetriones as Ca(V)1.3 calcium channel-selective antagonists for Parkinson's disease.

Pub. Date : 2013 Jun 13

PMID : 23651412






2 Functional Relationships(s)
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1 We recently identified pyrimidinetriones (PYTs) as a CaV1.3-selective scaffold; here we report the structure-activity relationship of PYTs with both CaV1.3 and CaV1.2 LTCCs. barbituric acid calcium voltage-gated channel subunit alpha1 D Homo sapiens
2 We recently identified pyrimidinetriones (PYTs) as a CaV1.3-selective scaffold; here we report the structure-activity relationship of PYTs with both CaV1.3 and CaV1.2 LTCCs. barbituric acid calcium voltage-gated channel subunit alpha1 D Homo sapiens