Protein Name calcium voltage-gated channel subunit alpha1 D
Organism Homo sapiens
Gene ID 776
Gene Symbol

CACNA1D

UniProt Q01668 (CAC1D_HUMAN), Q59GD8 (Q59GD8_HUMAN), A0A1B0GUN6 (A0A1B0GUN6_HUMAN)
Relationships Total Number of functionally related compound(s) : 97
Total Number of Articles : 132
Description

calcium voltage-gated channel subunit alpha1 D

Gene Summary

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

synonyms
  • voltage-dependent L-type calcium channel subunit alpha-1D
  • calcium channel, L type, alpha-1 polypeptide
  • calcium channel, neuroendocrine/brain-type, alpha 1 subunit
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Properties