Title : Curcumin inhibits LPS-induced inflammation in rat vascular smooth muscle cells in vitro via ROS-relative TLR4-MAPK/NF-κB pathways.

Pub. Date : 2013 Jul

PMID : 23645013






1 Functional Relationships(s)
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1 The LPS-induced overexpression of MCP-1 and TNF-alpha, and NO production were attenuated by pretreatment with the ERK inhibitor PD98059, the p38 MAPK inhibitor SB203580, the NF-kappaB inhibitor PDTC or anti-TLR4 antibody, but not with the JNK inhibitor SP600125. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one tumor necrosis factor Rattus norvegicus