Pub. Date : 2013 May 20
PMID : 23642142
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Human copper transporter 1 (hCTR1) facilitates the cellular uptake of cisplatin, and the extracellular N-terminal domain has been proven to coordinate to platinum drugs. | Cisplatin | solute carrier family 31 member 1 | Homo sapiens |
2 | Human copper transporter 1 (hCTR1) facilitates the cellular uptake of cisplatin, and the extracellular N-terminal domain has been proven to coordinate to platinum drugs. | Cisplatin | solute carrier family 31 member 1 | Homo sapiens |
3 | It has been reported that the intracellular C-terminal motif is crucial for the function of hCTR1 in cisplatin influx. | Cisplatin | solute carrier family 31 member 1 | Homo sapiens |
4 | This result indicates that hCTR1 can transfer cisplatin in the active form through a trans chelation process. | Cisplatin | solute carrier family 31 member 1 | Homo sapiens |