Title : Interaction between platinum complexes and the C-terminal motif of human copper transporter 1.

Pub. Date : 2013 May 20

PMID : 23642142






4 Functional Relationships(s)
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Protein Name
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1 Human copper transporter 1 (hCTR1) facilitates the cellular uptake of cisplatin, and the extracellular N-terminal domain has been proven to coordinate to platinum drugs. Cisplatin solute carrier family 31 member 1 Homo sapiens
2 Human copper transporter 1 (hCTR1) facilitates the cellular uptake of cisplatin, and the extracellular N-terminal domain has been proven to coordinate to platinum drugs. Cisplatin solute carrier family 31 member 1 Homo sapiens
3 It has been reported that the intracellular C-terminal motif is crucial for the function of hCTR1 in cisplatin influx. Cisplatin solute carrier family 31 member 1 Homo sapiens
4 This result indicates that hCTR1 can transfer cisplatin in the active form through a trans chelation process. Cisplatin solute carrier family 31 member 1 Homo sapiens