Title : Gastroesophageal reflux activates the NF-κB pathway and impairs esophageal barrier function in mice.

Pub. Date : 2013 Jul 1

PMID : 23639809






2 Functional Relationships(s)
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1 In a second animal experiment, treatment with an NF-kappaB inhibitor, BAY 11-7085 (20 mg kg-1 day-1 ip for 10 days), counteracted the effects of duodenal and mixed reflux on epithelial resistance and NF-kappaB-regulated cytokines. BAY 11-7085 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 In a second animal experiment, treatment with an NF-kappaB inhibitor, BAY 11-7085 (20 mg kg-1 day-1 ip for 10 days), counteracted the effects of duodenal and mixed reflux on epithelial resistance and NF-kappaB-regulated cytokines. BAY 11-7085 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus