Title : BDNF and CREB1 genetic variants interact to affect antidepressant treatment outcomes in geriatric depression.

Pub. Date : 2013 Jun

PMID : 23619509






2 Functional Relationships(s)
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1 SNPs at the CREB1 locus, which encodes a transcription factor important in BDNF signaling, also predicted response to paroxetine. Paroxetine cAMP responsive element binding protein 1 Homo sapiens
2 Furthermore, we found a significant gene-gene interaction between BDNF and CREB1 that affected response to paroxetine. Paroxetine cAMP responsive element binding protein 1 Homo sapiens