Title : EGFR cooperates with glucose transporter SGLT1 to enable chromatin remodeling in response to ionizing radiation.

Pub. Date : 2013 May

PMID : 23602371






3 Functional Relationships(s)
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1 The aim of this study was to elucidate the role of EGFR in glucose uptake and chromatin remodeling. Glucose epidermal growth factor receptor Homo sapiens
2 RESULTS: EGFR/SGLT1 interactions in response to ionizing radiation were associated with increased glucose uptake. Glucose epidermal growth factor receptor Homo sapiens
3 CONCLUSIONS: Radiation-associated interactions between SGLT1 and EGFR resulted in increased glucose uptake, which counteracts the ATP crisis in tumor cells due to chromatin remodeling. Glucose epidermal growth factor receptor Homo sapiens