Pub. Date : 2013 Oct
PMID : 23589096
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DeltaNp63alpha represses nuclear translocation of PTEN by inhibition of NEDD4-1 in keratinocytes. | deltanp63alpha | phosphatase and tensin homolog | Homo sapiens |
| 2 | The goal of this study was to define the mechanisms by which DeltaNp63alpha mediates the nuclear exclusion of PTEN. | deltanp63alpha | phosphatase and tensin homolog | Homo sapiens |
| 3 | We demonstrate here that DeltaNp63alpha reduces the ubiquitination of PTEN, a key signaling event in the nuclear translocation of PTEN. | deltanp63alpha | phosphatase and tensin homolog | Homo sapiens |
| 4 | We demonstrate here that DeltaNp63alpha reduces the ubiquitination of PTEN, a key signaling event in the nuclear translocation of PTEN. | deltanp63alpha | phosphatase and tensin homolog | Homo sapiens |
| 5 | The decrease in ubiquitinated PTEN correlated with the ability of DeltaNp63alpha to bind to neuronal precursor developmentally down regulated 4 (NEDD4) promoter and transcriptionally repress the E3 ubiquitin ligase NEDD4-1. | deltanp63alpha | phosphatase and tensin homolog | Homo sapiens |