Title : Gastrodin stimulates anticancer immune response and represses transplanted H22 hepatic ascitic tumor cell growth: Involvement of NF-κB signaling activation in CD4+ T cells.

Pub. Date : 2013 Jun 15

PMID : 23578476






4 Functional Relationships(s)
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1 Gastrodin stimulates anticancer immune response and represses transplanted H22 hepatic ascitic tumor cell growth: Involvement of NF-kappaB signaling activation in CD4+ T cells. gastrodin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 Gastrodin administration specifically upregulated mRNA levels of several nuclear factor kappaB (NF-kappaB) responsive genes in CD4+ T cells but not in CD8+ T cells. gastrodin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
3 Gastrodin administration specifically upregulated mRNA levels of several nuclear factor kappaB (NF-kappaB) responsive genes in CD4+ T cells but not in CD8+ T cells. gastrodin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
4 Chromatin immunoprecipitation assay showed that gastrodin increased the association of NF-kappaB p65 subunit to the promoter regions of IL-2 and Bcl-2 encoding genes in CD4+ T cells. gastrodin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus