Title : Vinblastine-induced apoptosis of melanoma cells is mediated by Ras homologous A protein (Rho A) via mitochondrial and non-mitochondrial-dependent mechanisms.

Pub. Date : 2013 Aug

PMID : 23564313






1 Functional Relationships(s)
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1 Also, vinblastine enhances the phosphorylation of Ras homologous protein A, the accumulation of reactive oxygen species, the release of intracellular Ca(2+), as well as the activation of apoptosis signal-regulating kinase 1, c-jun-N-terminal kinase, p38, inhibitor of kappaBalpha (IkappaBalpha) kinase, and inositol requiring enzyme 1alpha. Vinblastine mitogen-activated protein kinase 14 Homo sapiens