Pub. Date : 2010 Sep
PMID : 23554653
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We also used Western blotting analysis to assess the effect of resveratrol on inducible nitric oxide synthase (iNOS) expression and nuclear factor-kappaB (NF-kappaB) translocation to the nuclei in cells treated with IL-1beta. | Resveratrol | nitric oxide synthase 2 | Rattus norvegicus |
| 2 | RESULTS: Resveratrol significantly suppressed IL-1beta-induced NO production, a finding that correlated well with reduced levels of iNOS mRNA and protein. | Resveratrol | nitric oxide synthase 2 | Rattus norvegicus |
| 3 | The molecular mechanism by which resveratrol inhibited iNOS gene expression appeared to involve increased PPAR-gamma activity, which resulted in the inhibition of NF-kappaB activation. | Resveratrol | nitric oxide synthase 2 | Rattus norvegicus |