Title : The effect of estrogen on prolidase-dependent regulation of HIF-1α expression in breast cancer cells.

Pub. Date : 2013 Jul

PMID : 23549681






1 Functional Relationships(s)
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1 However, in MDA-MB-231 cells (expressing high prolidase activity) cultured in the presence of prolidase substrates, Gly-Pro or Gly-HyPro, HIF-1alpha expression was induced in a dose-dependent manner, independently of estrogen receptor activation. Glycine hypoxia inducible factor 1 subunit alpha Homo sapiens