Title : Chronological changes and effects of AMP-activated kinase in the hippocampal CA1 region after transient forebrain ischemia in gerbils.

Pub. Date : 2013 May

PMID : 23540408






2 Functional Relationships(s)
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1 CONCLUSION: These results suggest that AMPK is transiently phosphorylated following forebrain ischemia in the hippocampal CA1 region and inhibition of AMPK has neuroprotective effects against ischemic damage through the reduction of ATP depletion and lactate accumulation in the hippocampal CA1 region. Lactic Acid protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 CONCLUSION: These results suggest that AMPK is transiently phosphorylated following forebrain ischemia in the hippocampal CA1 region and inhibition of AMPK has neuroprotective effects against ischemic damage through the reduction of ATP depletion and lactate accumulation in the hippocampal CA1 region. Lactic Acid protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens