Title : Interferon-γ promoter is hypermethylated in blood DNA from workers with confirmed diisocyanate asthma.

Pub. Date : 2013 Jun

PMID : 23535363






1 Functional Relationships(s)
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1 Results showed that relative methylation of IFN-gamma promoter was significantly increased in DA+ in comparison with both comparator groups (DA- and AW), and it exhibited good sensitivity (77.5%) and specificity (80%) for identifying DA workers in a multivariate predictive model after adjusting for type of DI exposure, smoking status, methacholine PC20, and gender. Methacholine Chloride interferon gamma Homo sapiens