Title : Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione.

Pub. Date : 2013 Jun

PMID : 23534396






3 Functional Relationships(s)
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1 Chronic GSH deficiency in old mice and elderly humans was associated with decreased fasted mitochondrial NEFA oxidation and insulin resistance, and these defects were reversed with GSH restoration. Glutathione insulin Homo sapiens
2 These data suggest that GSH is a novel regulator of mitochondrial NEFA oxidation and insulin resistance in aging. Glutathione insulin Homo sapiens
3 Chronic GSH deficiency promotes impaired NEFA oxidation and insulin resistance, and GSH restoration reverses these defects. Glutathione insulin Homo sapiens