Title : Inhibition of serine palmitoyltransferase reduces Aβ and tau hyperphosphorylation in a murine model: a safe therapeutic strategy for Alzheimer's disease.

Pub. Date : 2013 Aug

PMID : 23528227






1 Functional Relationships(s)
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1 We previously reported that increased ceramide levels, regulated by increased serine palmitoyltransferase (SPT), directly mediate amyloid beta (Abeta) levels. Ceramides amyloid beta (A4) precursor protein Mus musculus