Pub. Date : 2013 Apr 15
PMID : 23490150
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An X-ray co-crystal structure of 19b with EGFR demonstrated that the N-1 and N-3 nitrogens of the pyrimido[4,5-b]azepine scaffold make hydrogen-bonding interactions with the main chain NH of Met793 and the side chain of Thr854 via a water-mediated hydrogen bond network, respectively. | Hydrogen | epidermal growth factor receptor | Homo sapiens |