Title : Inhibition of extracellular signal-regulated kinase activity by sorafenib increases sensitivity to DNR in K562 cells.

Pub. Date : 2013 May

PMID : 23467984






1 Functional Relationships(s)
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1 Of note, sorafenib sensitized K562 to DNR by inhibiting proliferation and inducing apoptosis in a dose-dependent manner which was through blocking the RAF/MEK/ERK pathway. Sorafenib zinc fingers and homeoboxes 2 Homo sapiens