Pub. Date : 2013 May 1
PMID : 23462309
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have found that HCB activates c-Src/HER1/STAT5b and HER1/ERK1/2 signaling pathways and cell migration, in an AhR-dependent manner in MDA-MB-231 breast cancer cells. | Hexachlorobenzene | aryl hydrocarbon receptor | Homo sapiens |
| 2 | Our results show that HCB (5muM) enhances MMP2 expression, as well as cell invasion, through AhR, c-Src/HER1 pathway and MMPs. | Hexachlorobenzene | aryl hydrocarbon receptor | Homo sapiens |
| 3 | Moreover, HCB increases MMP9 expression, secretion and activity through a HER1 and AhR-dependent mechanism, in MDA-MB-231 cells. | Hexachlorobenzene | aryl hydrocarbon receptor | Homo sapiens |