Title : Selenium is inversely associated with interleukin-6 in the elderly.

Pub. Date : 2013 Mar

PMID : 23459983






8 Functional Relationships(s)
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1 Selenium is inversely associated with interleukin-6 in the elderly. Selenium interleukin 6 Homo sapiens
2 In this study, we aim to investigate the association between serum selenium and the inflammatory cytokine interleukin-6 in the elderly living in long-term care facilities in Taiwan. Selenium interleukin 6 Homo sapiens
3 Multiple logistic and linear regression analyses were used to examine the relationships between selenium deficiency and interleukin-6 (divided into quartiles). Selenium interleukin 6 Homo sapiens
4 After adjusting for potential confounders using multiple logistic regression analysis, interleukin-6 quartiles were significantly associated with selenium deficiency. Selenium interleukin 6 Homo sapiens
5 Compared to the interleukin-6 quartile I, the adjusted odds ratios of having selenium deficiency for interleukin-6 quartile II, III, IV were 1.00(0.50~2.01), 1.24 (0.62~2.50), and 2.35(1.15~4.83), respectively. Selenium interleukin 6 Homo sapiens
6 The increasing odds ratios for selenium deficiency in higher interleukin-6 quartiles revealed dose-response effects (p < 0.05). Selenium interleukin 6 Homo sapiens
7 Moreover, multiple linear regression analysis showed that serum selenium was significantly inversely associated with interleukin-6 after adjusting for potential confounders. Selenium interleukin 6 Homo sapiens
8 CONCLUSIONS: Serum selenium was inversely associated with inflammatory cytokine interleukin-6 among elderly living in long-term care facilities in Taiwan. Selenium interleukin 6 Homo sapiens