Title : The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis.

Pub. Date : 2013 Jun

PMID : 23446148






3 Functional Relationships(s)
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1 Lastly, post-translational acetylation of key lysine residues within NLSs of HMGB1 affects HMGB1 to promote inflammation; hyperacetylation of HMGB1 shifts its equilibrium from a predominant nuclear location toward a cytosolic and subsequent extracellular presence. Lysine high mobility group box 1 Homo sapiens
2 Lastly, post-translational acetylation of key lysine residues within NLSs of HMGB1 affects HMGB1 to promote inflammation; hyperacetylation of HMGB1 shifts its equilibrium from a predominant nuclear location toward a cytosolic and subsequent extracellular presence. Lysine high mobility group box 1 Homo sapiens
3 Lastly, post-translational acetylation of key lysine residues within NLSs of HMGB1 affects HMGB1 to promote inflammation; hyperacetylation of HMGB1 shifts its equilibrium from a predominant nuclear location toward a cytosolic and subsequent extracellular presence. Lysine high mobility group box 1 Homo sapiens