Title : Anti-inflammatory and anti-allergic activities of Pentaherb formula, Moutan Cortex (Danpi) and gallic acid.

Pub. Date : 2013 Feb 25

PMID : 23439564






2 Functional Relationships(s)
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1 PHF, DP and GA could significantly suppress the expression of allergic inflammatory cytokine IL-33-upregulated intercellular adhesion molecule (ICAM)-1, and the release of chemokines CCL2, CCL5, CXCL8 and inflammatory cytokine IL-6 from KU812 cells (all p < 0.05). Gallic Acid interleukin 6 Homo sapiens
2 With the combined use of dexamethasone (0.01 mug/mL) and GA (10 mug/mL), the suppression of ICAM-1 expression and CCL5 and IL-6 release of IL-33-activated KU812 cells were significantly greater than the use of GA alone (all p < 0.05). Gallic Acid interleukin 6 Homo sapiens