Title : 7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies.

Pub. Date : 2013 Feb 20

PMID : 23429378






1 Functional Relationships(s)
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1 A structural series of 7-MEOTA-adamantylamine thioureas was designed, synthesized and evaluated as inhibitors of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBChE). 7-meota-adamantylamine thioureas butyrylcholinesterase Homo sapiens