Pub. Date : 2013 Apr
PMID : 23421317
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | AIM: Investigate the association between Dihydrofolate reductase (DHFR) 19-base pair (bp) deletion and Serine hydroxymethyltransferase (SHMT) C1420T polymorphisms and serum folate and plasma Hcy and methylmalonic acid (MMA) concentrations in 85 individuals with DS. | Methylmalonic Acid | serine hydroxymethyltransferase 1 | Homo sapiens |
2 | AIM: Investigate the association between Dihydrofolate reductase (DHFR) 19-base pair (bp) deletion and Serine hydroxymethyltransferase (SHMT) C1420T polymorphisms and serum folate and plasma Hcy and methylmalonic acid (MMA) concentrations in 85 individuals with DS. | Methylmalonic Acid | serine hydroxymethyltransferase 1 | Homo sapiens |
3 | RESULTS: Individuals with DHFR DD/SHMT TT genotypes presented increased folate concentrations (p=0.004) and the DHFR II/SHMT TT genotypes were associated with increased MMA concentrations (p=0.008). | Methylmalonic Acid | serine hydroxymethyltransferase 1 | Homo sapiens |