Pub. Date : 2013 Feb
PMID : 23420099
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, the mRNA levels of ABCC2, MSH2 and DPYD showed a strong correlation ( r >0.7) with the IC(50) values for CDDP. | Cisplatin | dihydropyrimidine dehydrogenase | Homo sapiens |
| 2 | In conclusion, mRNA levels of SLC22A2, SLC23A2, ABCB1, ABCC2, Rad51, MSH2 and DPYD were confirmed to be strongly correlated with IC50 values for 5-FU, and mRNA levels of ABCC2, MSH2 and DPYD were confirmed to be strongly correlated with IC(50) values for CDDP. | Cisplatin | dihydropyrimidine dehydrogenase | Homo sapiens |
| 3 | In addition, the inhibition of DPYD appeared to affect the cytotoxicity of CDDP. | Cisplatin | dihydropyrimidine dehydrogenase | Homo sapiens |