Title : The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells.

Pub. Date : 2013 Apr 26

PMID : 23402939






2 Functional Relationships(s)
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1 Effects of 96 h aflatoxin B1 (AFB1) exposure at concentrations from 0.2 muM to 6 muM on the mRNA and protein expression levels of the following transporters ABCB1/B4, ABCC1, ABCC2, ABCG2, OAT4 and the mRNA expression of steroid-metabolizing enzymes CYP1A1, CYP19A1, HSD3B1 and HSD17B1, and conjugating enzyme family UGT1A were evaluated in trophoblastic JEG-3 cells. Aflatoxin B1 cytochrome P450 family 1 subfamily A member 1 Homo sapiens
2 Effects of 96 h aflatoxin B1 (AFB1) exposure at concentrations from 0.2 muM to 6 muM on the mRNA and protein expression levels of the following transporters ABCB1/B4, ABCC1, ABCC2, ABCG2, OAT4 and the mRNA expression of steroid-metabolizing enzymes CYP1A1, CYP19A1, HSD3B1 and HSD17B1, and conjugating enzyme family UGT1A were evaluated in trophoblastic JEG-3 cells. Aflatoxin B1 cytochrome P450 family 1 subfamily A member 1 Homo sapiens