Title : Synthesis and biological evaluation of guanidino analogues of roscovitine.

Pub. Date : 2013 Apr

PMID : 23399722






1 Functional Relationships(s)
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1 A series of 2,9-substituted 6-guanidinopurines, structurally related to the cyclin-dependent kinase (CDK) inhibitors olomoucine and roscovitine, has been synthesized and characterized. Roscovitine cyclin dependent kinase 1 Homo sapiens