Title : Sensitization of lung cancer cells to cisplatin by β-elemene is mediated through blockade of cell cycle progression: antitumor efficacies of β-elemene and its synthetic analogs.

Pub. Date : 2013 Mar

PMID : 23397083






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 This was associated with upregulated checkpoint kinase (CHK2) expression and reduced CDC2 activity (i.e., increased phosphorylation of CDC2 on Tyr-15 and decreased phosphorylation of CDC2 on Thr-161). Tyrosine cyclin dependent kinase 1 Homo sapiens
2 This was associated with upregulated checkpoint kinase (CHK2) expression and reduced CDC2 activity (i.e., increased phosphorylation of CDC2 on Tyr-15 and decreased phosphorylation of CDC2 on Thr-161). Tyrosine cyclin dependent kinase 1 Homo sapiens