Title : The effect of phosphate binders, calcium and lanthanum carbonate on FGF23 levels in chronic kidney disease patients.

Pub. Date : 2013 Jul

PMID : 23391319






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1 The effect of phosphate binders, calcium and lanthanum carbonate on FGF23 levels in chronic kidney disease patients. lanthanum carbonate fibroblast growth factor 23 Homo sapiens
2 The aim of this study is to compare the effectiveness of calcium carbonate vs. lanthanum carbonate in reducing serum FGF23 levels in Chronic Kidney Disease (CKD) patients. lanthanum carbonate fibroblast growth factor 23 Homo sapiens
3 RESULTS: As compared with calcium carbonate, patients on lanthanum carbonate had lower serum levels of FGF23 (226 +- 11 vs. 158 +- 9 pg/ml) and less urinary excretion of phosphate. lanthanum carbonate fibroblast growth factor 23 Homo sapiens
4 CONCLUSIONS: In conclusion, in CKD 4 - 5 patients lanthanum carbonate is effective in reducing phosphate load and FGF23 levels; this effect was not observed with calcium carbonate. lanthanum carbonate fibroblast growth factor 23 Homo sapiens