Title : 5-Fluorouracil induces diarrhea with changes in the expression of inflammatory cytokines and aquaporins in mouse intestines.

Pub. Date : 2013

PMID : 23382968






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1 In the present study, the expressions of mRNAs that encode inflammatory cytokines, TNF-alpha, IL-1beta, IL-6, Il-17A and IL-22, were significantly increased throughout the entire colon of mice that exhibited diarrhea following 5-FU administration. Fluorouracil tumor necrosis factor Mus musculus