Title : U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.

Pub. Date : 2013 Apr 1

PMID : 23376934






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The essential pre-mRNA splicing factor U2AF(65) is faced with the paradoxical tasks of accurately targeting polypyrimidine (Py) tracts preceding 3" splice sites while adapting to both cytidine and uridine nucleotides with nearly equivalent frequencies. polypyrimidine U2 small nuclear RNA auxiliary factor 2 Homo sapiens