Pub. Date : 2013 May 1
PMID : 23376738
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. | Cysteine | cystathionine beta-synthase | Homo sapiens |
| 2 | Moreover, pre-treatment with aminooxyacetic acid, the inhibitor of CBS or knockdown of CBS in using siRNA, significantly attenuated the effects of L-cysteine on elevated H2S levels and the cell proliferation; it also effectively suppressed L-cysteine-induced neurogenesis and astrocytogenesis. | Cysteine | cystathionine beta-synthase | Homo sapiens |
| 3 | Moreover, pre-treatment with aminooxyacetic acid, the inhibitor of CBS or knockdown of CBS in using siRNA, significantly attenuated the effects of L-cysteine on elevated H2S levels and the cell proliferation; it also effectively suppressed L-cysteine-induced neurogenesis and astrocytogenesis. | Cysteine | cystathionine beta-synthase | Homo sapiens |
| 4 | Moreover, pre-treatment with aminooxyacetic acid, the inhibitor of CBS or knockdown of CBS in using siRNA, significantly attenuated the effects of L-cysteine on elevated H2S levels and the cell proliferation; it also effectively suppressed L-cysteine-induced neurogenesis and astrocytogenesis. | Cysteine | cystathionine beta-synthase | Homo sapiens |
| 5 | Taken together, the present data suggest that L-cysteine can enhance proliferation and differentiation of NSCs via the CBS/H2S pathway, which may serve as a useful inference for elucidating its role in regulating the fate of NSCs in physiological and pathological settings. | Cysteine | cystathionine beta-synthase | Homo sapiens |