Title : Stimulation of platelet death by vancomycin.

Pub. Date : 2013

PMID : 23363637






2 Functional Relationships(s)
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1 RESULTS: A 30 minutes exposure to vancomycin (>=1 microg/ ml) decreased cell volume, triggered annexin V-binding, increased [Ca(2+)]i, activated caspase 3, stimulated ceramide formation, triggered release of thromboxane B2, and upregulated surface expression of CD62P (P-selectin) as well as activated integrin alphallbbeta3. Vancomycin selectin P Homo sapiens
2 RESULTS: A 30 minutes exposure to vancomycin (>=1 microg/ ml) decreased cell volume, triggered annexin V-binding, increased [Ca(2+)]i, activated caspase 3, stimulated ceramide formation, triggered release of thromboxane B2, and upregulated surface expression of CD62P (P-selectin) as well as activated integrin alphallbbeta3. Vancomycin selectin P Homo sapiens