Title : Differentiation-inducing factor-1 suppresses the expression of c-Myc in the human cancer cell lines.

Pub. Date : 2013

PMID : 23357875






1 Functional Relationships(s)
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1 Pretreatment with the proteasome inhibitor MG132 or glycogen synthase kinase-3beta (GSK-3beta) inhibitors (LiCl and SB216763) attenuated the effect of DIF-1, suggesting that DIF-1 induced c-Myc protein degradation through GSK-3beta activation. benzyloxycarbonylleucyl-leucyl-leucine aldehyde glycogen synthase kinase 3 beta Homo sapiens